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2-Naphthylamine
N8381 -
powder
DOWNLOAD MSDS (PDF)Synonym: β-Naphthylamine, 2-Aminonaphthalene
CAS Number: 91-59-8
Linear Formula: C10H7NH2
Molecular Weight: 143.19
Beilstein Registry Number: 3939429
EC Number: 202-080-4
MDL number: MFCD00004112
PubChem Substance ID: 24897863
Properties
| Related Categories | Cancer Research, Carcinogens |
| form | powder |
| bp | 306 °C(lit.) |
| mp | 111-113 °C(lit.) |
| density | 1.061 g/mL at 25 °C(lit.) |
Description
Biochem/physiol Actions
Environmental carcinogen; induces bladder cancer.
Price and Availability
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Documents
Certificate of Analysis
Certificate of Origin
| Structure Search |  |
| Pressure-Temperature Nomograph |  |
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Safety Information
| Symbol |    GHS07, GHS08, GHS09 |
| Signal word | Danger |
| Hazard statements | H302-H350-H411 |
| Precautionary statements | P201-P273-P308 + P313 |
| Personal Protective Equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,N |
| Risk Statements | 45-22-51/53 |
| Safety Statements | 53-45-61 |
| RIDADR | UN 1650 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | QM2100000 |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
Articles
Carcinogenesis and Epigenetics
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Transcription, transformation
References
Ohnishi, S., et al., Oxidative DNA damage induced by a metabolite of 2-naphthylamine, a smoking-related bladder carcinogen. Jpn. J. Cancer Res. 93, 736-743, (2002) Abstract
Yasunaga, Y., et al., Alterations of the p53 gene in occupational bladder cancer in workers exposed to aromatic amines. Lab. Invest. 77, 677-684, (1997) Abstract
Merck 14,6399
Beil. 12,1265
Aldrich MSDS 1, 95:C / Corp MSDS 1 (1), 197:A / IR-Spectra (3), 748:H / IR-Spectra (2), 657:F / RegBook 1 (1), 1445:J / Sax 6, 1977 / Sigma FT-IR 1 (2), 768:B / Structure Index 1, 225:B:8
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